CBD effects on symptoms of diseases, on the endocannabinoid system and other receptors
But what effect does CBD actually have on the metabolic processes in the body? What are the CBD effects on symptoms of diseases and the endocannabinoid system? This and much more you will find out here.
The best research is currently on the effect of CBD on the endocannabinoid system (ECS). This is a network in the nervous system of the human body that works with receptors and enzymes.
We do not know yet what exactly is going on. It is clear, however, that this system inhibits severe stimuli, pain and also inflammation and affects numerous processes, such as appetite, sleep behavior and mood.
Active ingredients of the hemp plant mainly affect two receptors, the cannabinoid receptor 1 and the cannabinoid receptor 2.
While THC mainly affects receptor 1, the CBD effect focuses on receptor 2. The human body contains high numbers of these receptors in the immune system, the gastrointestinal system, the spleen, the tonsils, the thymus gland and the brain.
Important: Experts now advise that pregnant and nursing women abstain from CBD. The reason: The baby’s endocannabinoid system should develop naturally without the influence of conventional painkillers.
CB2 receptors cause an enormous range of medicinal properties of cannabis as they carry the responsibility for reducing inflammation, one of the main causes of a variety of diseases and conditions.
We can find these CB2 receptors in high concentrations in the gastrointestinal system, immune system, spleen, tonsils, thymus gland and brain. When CBD hits these receptors, it inhibits inflammation.
Anandamide: The Lucky Charm
In addition, CBD ensures that anandamide stays longer in the synapses of nerve cells. The functions of this body’s own substance have not yet been fully clarified.
The name derives from the Sanskrit word “Ananda”, which means bliss. It is clear that anandamide has many desirable effects. In this way, it fights anxiety and strengthens motivation.
CBD prevents fatty acid amide hydrolase (FAAH) from degrading anandamide. In addition, it combines with transport proteins that transfer anandamide out of the synapses. As a result, anandamide can have an irritant on nerve cells for much longer.
Furthermore, CBD involves in other processes: It acts on the 5-HT1A receptor, a component of the serotonin pathway.
This CBD effect helps with depression and sleep disorders. The ion channels of type TRPV1, also known as vanilloid receptors, are effective for pain and inflammation.
CBD effect in cells
The effect of CBD on the receptor GPR55 is still somewhat nebulous. This atypical cannabinoid receptor in the central nervous system was only discovered in 2007.
He appears to be involved in the transmission of pain and is likely to prevent epileptic seizures. The PPAR receptor system also affects CBD.
The main location of these receptors is in the nuclei and control numerous metabolic processes, including the processing of sugar and fat burning.
This means that CBD is active in addition to the signaling pathways controlled by enzymes, but also directly in the cells.
About the CBD effect on symptoms of diseases
Scientists around the world have been working hard for several years to clarify what effects CBD has in various diseases, and how we can use it as a cure.
This cannabidiol turns out to be almost a miracle cure with few harmless side effects. Perhaps we can explain the range of positive effects of CBD due to the fact that medicinal hemp becomes active throughout the body.
It affects the nervous system, metabolism and psyche as well as muscles and even works in the cells.
The following effects of CBD are scientifically well documented:
1- Relieves pain
2- Inhibits inflammation
3- Decluttering muscles
4- Acts mood-enhancing
5- Reduces nausea
6- Reduces fears
CBD effect in autoimmune diseases
As CBD fights inflammation throughout the body, it can alleviate symptoms in all autoimmune diseases, such as in people with Hashimoto thyroiditis or rheumatoid arthritis.
When misguided cells of the immune system attack the body’s own tissues, chronic this results in inflammation. Particularly interesting: It has now been proven that CBD has a balancing effect on the entire immune system.
CBD and inflammatory bowel disease
CBD has become particularly helpful in chronic inflammatory bowel diseases, such as ulcerative colitis.
Back in 2013, scientists at Tel Aviv University conducted a study of patients with Crohn’s disease. One year later, researchers at the University of Graz (Austria) confirmed the results: CBD can indeed significantly improve the symptoms of patients with Crohn’s disease.
CBD and type 1 diabetes
In type 1 diabetes, immune system cells attack the pancreas, causing chronic inflammation. Canadian scientists observed in 2016 that CBD effectively reduces inflammation of the pancreas.
Ten years earlier, however, it had only been shown in animal experiments that CBD can even prevent type 1 diabetes.
CBD and depression
The effect of CBD on mood is not negligible, especially in people with autoimmune diseases. The gentle active ingredient of the hemp plant can not only resolve anxiety, but it can also eliminate the cause of depression. It has now been proven that depression promotes the development of autoimmune diseases.
CBD: Worth a try
Meanwhile, you can read in numerous sources what CBD can do. However, a lot of information can be found on the websites of manufacturers of CBD products.
The objectivity of these source texts can rightly be questioned. Although many questions remain unanswered about the CBD effect, there is now no doubt that CBD relieves pain and inhibits inflammation – without the dangerous side effects of classic drugs.
These two effects of CBD alone make medicinal hemp interesting for every sick person – except for pregnant and nursing women. Although dosages are difficult to determine so far, CBD is worth a trial for anyone with autoimmune diseases.
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